Are Calendula and Mullein in the same botanical family?

No — Calendula is Asteraceae and Mullein is Scrophulariaceae.

Can you substitute Calendula for Mullein?

They come from different families (Asteraceae and Scrophulariaceae), so direct substitution is uncommon.

Compare · per-herb profile

Calendula vs Mullein

Calendula officinalis · Verbascum thapsus

Calendula

Calendula officinalis

T Traditional Use

Family: Asteraceae
Genus: Calendula
Primary use: medicinal

Calendula officinalis, Mary's gold, common marigold, the pot marigold, Scotch marigold, or ruddles, is a flowering plant in the daisy family, Asteraceae. It is probably native to southern Europe, but its long history of cultivation makes its precise origin unknown, and it is wide…

Mullein

Verbascum thapsus

T Traditional Use

Family: Scrophulariaceae
Genus: Verbascum
Primary use: medicinal

Verbascum thapsus, the great mullein, greater mullein or common mullein, is a species of mullein native to Europe, northern Africa, and Asia, and introduced in the Americas, Australia and New Zealand.

At a glance

· Different families — Asteraceae vs Scrophulariaceae.
· Both are primarily medicinal.
· Evidence tiers — Calendula: T; Mullein: T.